Mounjaro to Wegovy dose conversionthe switching map, worked out honestly
Here is the thing nobody selling you a neat conversion chart will say: there isn't one. No regulator publishes an equivalence between Mounjaro and Wegovy, in either direction, injection or tablets. What does exist is each medicine's published dose ladder. This planner lines those ladders up, shows which stage you're on, and gives you the two options a prescriber actually weighs: restart, or join at the same stage.
Dose ladders from the official UK labels (SmPCs). Works both directions, and covers the Wegovy tablets.
The short answer
There is no official Mounjaro to Wegovy dose conversion. Neither the MHRA nor the FDA publishes an mg-to-mg equivalence between tirzepatide (Mounjaro) and semaglutide (Wegovy). The closest safe comparison is ladder position: Mounjaro 10 mg, the Wegovy 2.4 mg injection and the 25 mg Wegovy tablet are all maintenance-stage doses. When you switch, a prescriber chooses between restarting the new medicine's ladder at its starting dose or joining it at your current stage. The planner below shows both options for any dose, in either direction.
A dose ladder is the fixed sequence of doses a medicine's licence sets out, from starting dose through titration to maintenance.
This is arithmetic on published dose ladders, not medical advice. There is no official conversion between these medicines, and this planner does not invent one. It lines the ladders up so you can see the shape of a switch. Your prescriber decides the actual dose and timing.
I currently take
My current dose
Switching to
10 mg weekly is the maintenance stage of the Mounjaro ladder. On Wegovy injection, a prescriber would usually be weighing up two places to land:
Option 1 · Restart the ladder
0.25 mg weekly
Restart the new medicine's own ladder at its starting dose and titrate up as its label describes. The slowest, gentlest option, and the only one some labels formally cover.
Option 2 · Join at the same stage
2.4 mg weekly
Join the new ladder at the maintenance stage, the position closest to where you are now. Where the map falls between steps, it shows the lower one.
Mounjaro ladder
- 2.5 mg weeklyStarting dose
- 5 mg weeklyTitration
- 7.5 mg weeklyTitration
- 10 mg weeklyMaintenanceYou are here
- 12.5 mg weeklyMaintenance
- 15 mg weeklyHigher maintenance
Wegovy injection ladder
- 0.25 mg weeklyStarting doseRestart
- 0.5 mg weeklyTitration
- 1 mg weeklyTitration
- 1.7 mg weeklyTitration
- 2.4 mg weeklyMaintenanceSame stage
- 7.2 mg weeklyHigher maintenance
Read before you talk to your prescriber
- No regulator publishes a conversion between these medicines. These options line up positions on the two published dose ladders, nothing more. They are not equivalent doses.
- Your prescriber makes the actual switching decision: which step to start on, whether to retitrate from the bottom, and how to time the changeover.
- Semaglutide and tirzepatide are different molecules. Tirzepatide works on two gut hormones (GIP and GLP-1), so there is no true mg-for-mg equivalence between them, only positions on each ladder.
- In trials (SURMOUNT vs STEP), tirzepatide produced more average weight loss than semaglutide, so an aligned step can feel like a step down in effect. Some appetite returning over the first few weeks is expected, not failure.
What about taking two forms at once?â–¾
You will see people online combining forms: tablets alongside a reduced injection dose, or tablets bridging a supply gap between injections. The usual reasons are price, availability and side effects.
This planner deliberately does not add doses across two forms. The mg scales are not comparable, so a combined total is exactly where home-made arithmetic gets dangerous. If combining forms is on your mind, take the question to your prescriber; that conversation is the whole plan, not a footnote to it.
The conversion chart, done properly
If you came here searching for a Mounjaro to Wegovy conversion chart, this is the honest version: the three UK ladders side by side, grouped by stage. Read across a row and you're comparing positions, not potency. The milligrams don't translate; the stages roughly do.
| Stage | Mounjaro (weekly) | Wegovy injection (weekly) | Wegovy tablets (daily) |
|---|---|---|---|
| Starting dose | 2.5 mg | 0.25 mg | 1.5 mg |
| Titration | 5 mg, 7.5 mg | 0.5 mg, 1 mg, 1.7 mg | 4 mg, 9 mg |
| Maintenance | 10 mg, 12.5 mg | 2.4 mg | 25 mg |
| Higher maintenance | 15 mg | 7.2 mg | — |
Why can't the milligrams translate? Two reasons. Tirzepatide (Mounjaro) is a different molecule from semaglutide (Wegovy), a dual-hormone drug with no mg-for-mg relationship to it. And the Wegovy tablet's numbers are inflated by absorption: only around 1% of a swallowed dose reaches your blood.
Do you really restart from the bottom?
This is the anxiety behind most switching searches, and the answer is: usually not, but sometimes yes. In practice, UK prescribers tend to start a switcher at the nearest step their body is likely to tolerate rather than the full beginner dose. Someone on 2.4 mg Wegovy rarely goes back to a 2.5 mg Mounjaro starting dose for four months of climbing; equally, they rarely jump straight to a top step of a molecule their body has never met.
The direction matters too. Moving from Wegovy to Mounjaro is usually a step up in effect, so prescribers lean cautious and pick a lower step than the stage map suggests. Moving from Mounjaro to Wegovy is the opposite: even the aligned step may feel weaker, and the first few weeks can bring appetite back. Neither is a reason to panic. It is a reason to plan the switch with the person prescribing it.
That's why the planner always shows two answers. The conservative restart is the option every label covers. The stage-aligned step is where many switchers actually land. The gap between them is the conversation to have at your next appointment.
Switching from the injection to the tablets
Since the Wegovy tablets went on sale in the UK in July 2026, a lot of switching questions are really route questions: same drug, different way in. The trial evidence is reassuring. In OASIS 4, the 25 mg tablet matched the 2.4 mg injection on weight-loss outcomes. What changes is the routine:
- Weekly becomes daily. One tablet every morning instead of one injection a week.
- The morning rules are strict: empty stomach, no more than 120 ml of plain water, then at least 30 minutes before food, other drinks or other oral medicines.
- Timing the changeover matters, because a weekly injection keeps working for weeks after the last dose. Your prescriber will tell you when the first tablet goes in; don't guess.
The mg numbers will look alarming (1.5 mg to 25 mg daily against 0.25 mg to 2.4 mg weekly) and that is normal. We've written up why the numbers sit on different scales in the mg confusion explainer.
Why people switch at all
Three reasons come up over and over: price, side effects and supply. Prices move month to month and differ by hundreds of pounds a year between pharmacies, which is why we keep a verified comparison on the GLP-1 price table (no pharmacy pays to appear). Side effects are personal: some stomachs simply get on better with one molecule than the other. And supply gaps still happen, though less often than in 2024.
One thing to keep an eye on rather than act on: orforglipron, a daily GLP-1 pill that needs no food or water rules, is licensed in the US and working through the UK pipeline. It isn't part of UK switching decisions yet.
Questions people actually ask
What is Wegovy 2.4 mg equivalent to on Mounjaro?
There is no official equivalent, and the mg numbers can't be compared directly because tirzepatide (Mounjaro) is a different molecule. What you can say: 2.4 mg is Wegovy's standard maintenance dose, and Mounjaro's ladder reaches its maintenance steps at 10 mg. Trials suggest tirzepatide is the stronger of the two step for step, so prescribers often start switchers lower, commonly at 5 mg, and titrate from there.
What is 1 mg Wegovy equivalent to in Mounjaro?
1 mg is a mid-titration dose on Wegovy's ladder. The matching stage on Mounjaro's ladder is the 5 mg step. That is a position match, not an equivalent dose: no regulator publishes a conversion between semaglutide and tirzepatide.
What does 10 mg Mounjaro convert to on Wegovy?
10 mg is a maintenance step on Mounjaro's ladder, so the matching stage is Wegovy's 2.4 mg injection maintenance dose, or the 25 mg tablet. Because tirzepatide produced more average weight loss in trials, moving across at the same stage can still feel like a step down in effect. Your prescriber decides the landing step.
Do I have to restart titration when I switch?
Not always from the very bottom. Prescribers usually start a switcher at the nearest tolerated step rather than the full beginner dose, but the labels differ by drug and by direction, and some prefer a full restart to protect your stomach. The planner shows both options so you can have that conversation properly.
Will I lose less weight after switching from Mounjaro to Wegovy?
On trial averages, tirzepatide outperformed semaglutide: roughly 21% of body weight in SURMOUNT-1 (2022) against 15% in STEP 1 (2021) at top doses. So some people notice appetite creeping back after this switch. That is expected, not failure, and plenty of people do well on Wegovy. Switching the other way, Wegovy to Mounjaro, is usually a step up in effect.
Is the 25 mg Wegovy pill the same as the 2.4 mg injection?
Not in mg terms. Only around 1% of a swallowed semaglutide tablet is absorbed, which is why the pill's numbers are so much bigger. But in the OASIS 4 trial the 25 mg tablet matched the 2.4 mg injection on weight-loss outcomes. Same drug, different route, matched on results rather than milligrams.
When do I take the first Wegovy tablet after my last injection?
Your prescriber sets the changeover. The usual pattern is starting the daily tablet around the time the next weekly injection would have been due, since the old dose is still tapering out of your body for weeks. The tablet also comes with strict morning rules: empty stomach, no more than 120 ml of plain water, then a 30-minute wait before food or other medicines.
Why is there no official conversion chart?
Because there is nothing exact to put in one. Semaglutide and tirzepatide are different molecules, tablets and injections absorb differently, and bioavailability varies from person to person. Neither the MHRA nor the FDA publishes a conversion, so any tidy mg-to-mg chart you see online is somebody's estimate. This page maps ladder stages instead, and says so plainly.
Sources
The dose ladders come straight from the official UK prescribing documents, and the trial figures from the published papers:
- Mounjaro (tirzepatide) Summary of Product Characteristics, emc: the UK dose ladder and titration rules.
- Wegovy (semaglutide) injection Summary of Product Characteristics, emc: the injection ladder, 0.25 mg to 2.4 mg.
- Wegovy 25 mg tablets Summary of Product Characteristics, emc: the tablet ladder and the morning rules.
- MHRA: first GLP-1 tablet for weight loss approved in the UK, gov.uk, June 2026: the tablets' UK licence.
- Tirzepatide once weekly for the treatment of obesity (SURMOUNT-1), NEJM 2022: the roughly 21% average weight loss figure.
- Once-weekly semaglutide in adults with overweight or obesity (STEP 1), NEJM 2021: the roughly 15% average weight loss figure.
- Oral semaglutide 25 mg in adults with overweight or obesity (OASIS 4), NEJM 2025: the tablet matching the injection on outcomes.
Switching is when tracking earns its keep
The weeks around a switch are exactly when appetite, side effects and weight wobble. Healthcount logs your dose, food and weight in one place and shows the trend line through the change, so you and your prescriber are looking at data, not guesswork.
Sign up freeKeep reading
Why the milligram numbers aren't comparable, explained properly.
Titration dates, refills and verified UK prices for the tablets.
Every verified UK price, no pharmacy pays to appear.
mg, mL and pen units for the UK KwikPen.